All products must be ordered through our website. All of our products are specialty compounded topical formulations or oral medications requiring the supervision of a physician. Accordingly, they require a physician’s prescription and are compounded by our licensed and accredited compounding pharmacy. You can either have your own healthcare provider write the prescription for you or one of our physicians can review your case and write prescriptions for you.

Your healthcare provider can either email us the prescription at info@compoundhair.com or call the prescription in to (435) 703-9680. Once we have the prescription, you will then be approved to go on to the website and order the product.

In order to be evaluated by one of our physicians, you need to complete an initial online consultation. One of our physicians then reviews your case, consults with you, and is able to start prescribing for you.

Yes, it does matter which state you live in. We have to be licensed in your state in order to send medication to you. 

Alaska, Arizona, California, Colorado, Florida, Georgia, Hawaii, Idaho, Indiana, Michigan, Minnesota, Missouri, Montana, Nevada, New Jersey, New Mexico, New York, North Carolina, South Carolina, Ohio, Oregon, Pennsylvania, Texas, Utah, Virginia, Washington, Wyoming.

Our pharmacy and compounding laboratory are government licensed and regulated and therefore you can be assured that the lab compounds all products according to licensing body regulations. Our physicians are all U.S. medical school graduates who are licensed to practice medicine in the United States. We have a brick and mortar location that you can stop by and see our pharmacists and techs compound medications. Visit us at 1100 N Canyon View Dr Suite C, Santa Clara UT. In fact, you could watch your prescription be compounded if you desired. You can meet with any of our licensed physicians to discuss your case and ask questions.

In contrast to our medical practice, you should actually be concerned if you order medications online from any entity that is not a government licensed and regulated facility with a brick and mortar building. And even more concerned if medications that require a physician prescription are being distributed without physician consultations. If no physical location is associated with the website/business, then the compounding standards it meets can not be guaranteed. In fact, it is very likely that it does not meet licensing requirements and therefore has no obligation whatsoever to ensure that the product you receive actually contains the medications you ordered. Any entity shipping medications ordered through a website should have a physical location that can be visited by both patients and government regulators. Failure to have this absolutely calls the legitimacy of the products shipped into question.

No. Photographs can be extremely subjective and with the advent of digital photography and programs such as Adobe Photoshop, they are so easy to retouch or ‘morph’ that they are the mainstay of scam artists who profess to grow hair. Compound’s philosophy has been that you are your own best judge and critic. If our treatments work well for you, you’ll use them. If they don’t, you won’t. Patient satisfaction and word of mouth, not photographs, substantiate Compound’s track record.

No. Such testimonials are even easier to fictionalize than are photographs. If you desire unbiased reports on our products, please review the peer-reviewed publications that we reference.

We are a medical practice. The same way that your doctor doesn’t offer a money back guarantee if the antibiotic doesn’t cure your child’s ear infection, we don’t offer money back guarantees on our products. 

The clinical research and evidence for our products are reported on this website. This evidence is robust enough that the FDA has approved these medications for the treatment of pattern hair loss. However, there are no guarantees in medicine. There are no medications that are 100% effective. Anyone offering guarantees on medical products is being disingenuous.

Prescription medications are never guaranteed in regards to their pharmacological reaction on any patient. There are too many biological variabilities to predict results. For example, penicillin may cure an infection in one patient, but may induce a serious allergic effect in another. We do not claim that our products will work successfully for all patients. However, we can guarantee that the products are properly compounded, using the finest medications available, and that medical literature supports their use.

Absolutely not. You should purchase what you want wherever it’s the least expensive for you. However, be aware that companies offering similar products at lower prices may doing so illegally if they do not require a physician’s prescription and compound in a licensed lab and thus are not bound to provide licensed, quality products. There is an expense to maintaining an accredited, licensed compounding pharmacy and this is reflected in the cost of our products.

Yes. During your initial consultation, any and all questions relating to your hair and the regrowth of hair are answered. If you have medical questions relating to your therapy after the initial consultation, e-mail info@compoundhair.com. 

Please email rx@rx-fusion.com and include your name, shipping information, products ordered, and any other related information/questions.

Minoxidil displays a dose-dependent effect with higher concentrations, improving the responsiveness and greater regrowth of hair. The higher the effective dose of minoxidil, the better the results, albeit there is not a directly proportional response and there is a point where no additional gains are seen.

As previously stated, minoxidil displays a dose-dependent effect with higher concentrations improving the responsiveness and greater regrowth of hair. Using standard compounding techniques, minoxidil in alcohol based solutions reach their saturation point at approximately 5%. After years of intensive research, exhaustive experimentation, assistance from consulting pharmaceutical biochemists and extensive clinical testing, Compound Hair Loss Solutions, LLC offers high concentration minoxidil solutions. 

An excellent study relating dosage to results was reported in this article: Olsen, EA, DeLong ER, Weiner MS. Dose-response study of topical minoxidil in male pattern baldness. J Am Acad Dermatol. 1986;15:30-37.  

Not necessarily. As previously noted, the increased efficacy of minoxidil in promoting hair growth is not directly proportional to the increases in the concentrations of minoxidil. There are diminishing returns. In fact, in a study reported in Skin Pharmacology [Skin Pharmacol 1997;10(4):206-20] it was shown that ‘minoxidil had biphasic effects on the proliferation and differentiation of normal human keratinocytes (NHK): Minoxidil stimulated NHK proliferation at micromolar doses, while antiproliferative, pro-differentiative and partially cytotoxic effects were observed with millimolar concentrations.’ In other words, too much minoxidil can become counter productive in promoting hair growth.

As a general rule, you should not begin treatment with a high concentration minoxidil solution.  Most patients should begin treatment with 5 or 6% minoxidil solutions and move to higher concentration solutions once efficacy with 5 or 6% solutions is confirmed.

If, after at least six months of treatment with either of these regimens, the improvement is not satisfactory, then the patient may want to consider the use of high concentration minoxidil solutions on those areas of the scalp with inadequate regrowth of hair.

The second reason why a patient should not begin treatment of MPB with high concentration solutions is because topical minoxidil can allow hair that is already in the telogen phase to shed before the end of the phase.  Although the hair is replaced with thicker hair shafts, the observation of increased shedding, however temporary, may have a psychologically damaging effect on those patients who are already traumatized by the balding process.

According to Remington’s Pharmaceutical Science (20th Edition), minoxidil is soluble to the extent of “1gm in 25ml alcohol” (4% solution). When the solution is acidified, for example by azelaic acid or phosphoric acid, the solubility is increased to approximately 5%. With the addition of propylene glycol or glycerin, a true 5% minoxidil solution can be stabilized.

Making a higher concentration minoxidil solution is much more complicated and the compounding technique remains a closely guarded trade secret. 

High concentration minoxidil solutions should be stored with the container’s cap tightly attached, at room temperature and out of direct sunlight.

Yes. For optimal results, it is recommended that male patients use high concentration minoxidil solutions in combination with an agent or agents that decrease the DHT in the scalp. High concentration minoxidil solutions can be used as the sole medication in the treatment of female pattern hair loss (FPHL), but should not be used by nursing mothers.

Minoxidil has to have a serum concentration of 20 ng/mL to have any hemodynamic or other systemic effect in the human body. Allowing for 1.7% absorption of minoxidil from topical application, a 2% minoxidil solution will result in 0.6 ng/ mL and a 5% minoxidil solution will result in 1.2 ng / mL of minoxidil in the serum. So, there is more than a 16-fold safety margin from the use of 5% topical minoxidil and a 5-fold safety margin with the use of a 15% topical minoxidil solution.

Yes. There is proportionately less propylene glycol in our formulations than there are in 5% Rogaine®/Regaine® and its generic equivalents. The ‘greasy’ feeling due to propylene glycol that is often associated with Extra Strength Rogaine®/Regaine® and their generic versions is not present when using Compound’s minoxidil solutions. However, propylene glycol can be quite irritating to the scalp for approximately 7% of the patients. To accommodate those patients who have untoward reactions to propylene glycol, we have formulated minoxidil solutions that substitute hypoallergenic glycerin for propylene glycol.

No. Both glycerin and propylene glycol are pharmacologically inactive ingredients in the minoxidil products. They are used in minoxidil solutions because (1) they are humectants, i.e. they help to moisturize the skin and help protect from the drying effect of the alcohol; (2) they increase and stabilize the solubility of minoxidil; and (3) they keep a small quantity of minoxidil on the surface of the scalp to allow for continued absorption after the alcohol necessary to the base solution has penetrated. 

The 5% and higher minoxidil solutions have the potential to promote regrowth of more hair and thicker hair, but they do not change the genetic properties of the hair follicles. Although the growth (anagen) phase may be lengthened, the dormant (telogen) phase of approximately 100 days is unchanged. In order to see results, the existing thin hair shafts need to be replaced with thicker ones. This is why it usually takes between 3 and 6 months to appreciate significant hair regrowth with any concentration of minoxidil solution of 2% or greater.

In the vast majority of patients there are no side effects. If side effects do occur, patients who have a known adverse reaction to minoxidil, should avoid using any minoxidil preparations. Although rare, patients who are sensitive to minoxidil can experience a rapid heart rate, a drop in blood pressure and water retention. As a result, they may experience headaches, dizziness, chest pain and/or edema of the ankles. If such side effects occur, these patients should discontinue any formulas containing minoxidil. In our experience, these side effects have occurred in less than 0.1% of patients.

These are skin reactions in the areas to which the minoxidil solution is directly applied. These reactions may include soreness, redness, irritation, drying or flaking, etc. It is unusual for minoxidil to cause any of these events. Any untoward reactions are almost always due to the propylene glycol.

Patients who have untoward reactions to minoxidil or to any of the ingredients in the base should not use high concentration minoxidil solutions. Also patients who are hypersensitive to the action of minoxidil should not use high concentration minoxidil solutions.

Side Effects: Patients with any history of heart disease should not use minoxidil without first consulting their physician. Also patients who have a known adverse reaction to minoxidil should avoid using our formulas. Although rare, patients who are sensitive to minoxidil can experience a rapid heart rate, a drop in blood pressure and water retention. As a result, they may experience headaches, dizziness, chest pain and/or edema of the ankles. If that happens, these patients should discontinue use of any formulas containing minoxidil. In our experience, these side effects have occurred in less than 0.1% of patients.

Yes. Topical minoxidil solutions are still treatments and are not cures for PHL. If you discontinue using minoxidil solutions, the scalp will revert to its baseline (before-use) condition in three to four months. However, some patients can achieve acceptable maintenance with once/day applications of higher concentration minoxidil formulas.

Not really. It’s important that the maximum amount of the medicated solutions be deposited on the scalp, so they can be absorbed into the dermis to the level of the hair follicle. There is essentially no effective delivery of medications through the hair shaft.

As a general rule, medications are more readily absorbed when the skin is hydrated. But minoxidil solutions can be applied to a dry scalp as well. Our recommendation is to apply the minoxidil solutions to a dry scalp or to the scalp that is at least towel dried in order to avoid dilution.

It would be advisable to blow-dry the hair before the application of our products. Otherwise, blow-drying will cause most of the product to evaporate rather than to absorb. Applying 1mL of product to the scalp should not significantly alter the appearance of one’s hairstyle.

No. Minoxidil must penetrate the scalp to work effectively at the level of the hair follicles. Shampoos and conditioners would have to contain very large amounts of alcohol and/or remain on the scalp for hours in order to transfer minoxidil through the scalp.

The certificate of analysis for minoxidil USP 24* states that it is a ‘whitish or slightly yellow crystal’. Depending upon the batch from which your minoxidil product was compounded, the color of your topical solution might vary from colorless to amber from shipment to shipment. The color difference does not alter the pharmacological or biological efficacy of your medicine.

There’s no simple answer. Whereas treatment is almost always more effective when the signs and symptoms of pattern hair loss are recent, we have patients in their 70’s who have had satisfactory results from combined treatment of topical minoxidil and a 5-alpha reductase inhibitor. In fact, hair regrowth was initially observed in older men in their 50’s or 60’s who were being treated with finasteride for enlarged prostates. That discovery was the impetus for developing Propecia®.

Ethyl alcohol is one of the few substances that freely permeates the skin (the permeability coefficient of ethanol across human skin in 8 x 10 –8 mol/cm2) and it transports the minoxidil and finasteride with it. The penetration enhancing effects of ethanol play a significant role in minoxidil absorption. The effective absorption of topical minoxidil and finasteride depends on the vehicle composition. Greater effects are achieved when the fraction of the volatile component increases, especially at ethanol concentrations higher than 50% (and maximizing at 90%).

When the alcohol has absorbed into the scalp, there will be a slight stickiness due to the residual glycerin and minoxidil. Topical finasteride is completely absorbed. This residual reservoir of minoxidil provides a beneficial source for the continued absorption (although relatively minimal) of minoxidil even after the product has dried on the scalp. If high concentration minoxidil solutions are only used at night and applied in small amounts, you can minimize the objections to the residual matter on the scalp, while you simultaneously maximize the absorption of minoxidil.

In a highly saturated solution of minoxidil, there may be occasions when a precipitate will form in the bottle. If and when this happens, the tightly capped bottle should be placed in a bath of water that has been heated to a gentle simmer, and shaken vigorously. As long as the bottle is kept tightly capped, it can be kept in heated water until all the minoxidil goes back into solution.

Yes. Apply 1mL of either solution once/day. The applications should be at least 8 hours apart. It does not matter which solution is used at any particular time of day.

In some cases, physicians will prescribe finsteride solutions for post-menopausal women. Please consult with your doctor prior to beginning such medications. Pre-menopausal women should not use finasteride.

Independent studies from other researchers (e.g. Rushton and Ramsay in an article in the British Journal of Medicine) have shown that topical finasteride lowers the serum by inhibiting the synthesis of DHT in the prostate. “A 0.05% formulation of topical finasteride was well absorbed and lowered the serum dihydrotestosterone concentration by up to 40%”.

Topical finasteride and dutasteride can be used as the sole treatment for treating MPB or as a supplement to patients who are already using oral finasteride, as oral finasteride 1mg/daily lowers the amount of DHT in the scalp by only 38% (Roger S. Rittmaster, M.D. at the American Academy of Dermatology (AAD) meeting in San Francisco, March 2000).